Eric Schadt, PhD

eric_shadt_webMember of the Science Advisory Board

Eric Schadt, PhD, is the CEO of SEMA4 Genomics, Inc. and a Founding Director of the Icahn Institute for Genomics and Multiscale Biology, Chair of the Department of Genetics and Genomics Sciences, and the Jean C. and James W. Crystal Professor of Genomics at the Icahn School of Medicine at Mount Sinai.

Dr. Schadt is an expert on the generation and integration of very large-scale sequence variation, molecular profiling and clinical data in disease populations for constructing molecular networks that define disease states and link molecular biology to physiology. He is known for calling for a shift in molecular biology toward a network-oriented view of living systems to complement the reductionist, single-gene approaches that currently dominate biology in order to model more accurately the complexity of biological systems. He has contributed to a number of discoveries relating to the genetic basis of common human diseases such as diabetes, obesity and Alzheimer’s disease

Before joining Mount Sinai, Dr. Schadt was Chief Scientific Officer at Pacific Biosciences. Previously, Dr. Schadt was Executive Scientific Director of Genetics at Rosetta Inpharmatics (a subsidiary of Merck & Co.) and a Senior Research Scientist at Roche Bioscience.

Dr. Schadt has published more than 250 peer-reviewed articles (click here) in leading scientific journals.

Dr. Schadt received a B.A. in applied mathematics and computer science from California Polytechnic State University; a M.A. in pure mathematics from University of California, Davis; and a Ph.D. in bio-mathematics from University of California, Los Angeles (requiring Ph.D. candidacy in both molecular biology and mathematics).

Media Links

Watch Dr. Schadt’s 2015 interview with Medscape discussing how he turns math into medicine and how he hopes to hasten clinical research and the search for cures.

Watch Dr. Schadt’s 2015 NYU Polytechnic School of Engineering Lynford Lecture “Constructing Predictive Models of Human Diseases via the Integration of Panomic and Clinical Data to Better Diagnose and Treat Patients.”

Dr. Schadt discusses what’s currently in the pipeline in terms of accumulating data about the human body—and what the future holds.

Dr. Schadt discusses what the mapping of the fetal genetic code means for you.

Dr. Schadt discusses the effects of meditation at molecular cellular levels.

Dr. Schadt discusses how advances in genetic testing are improving cancer treatment.

Dr. Schadt discusses what big data means for patients, payers, and pharma.

Dr. Schadt discusses the continuous integration of big data into the field of medicine.

Dr. Schadt discusses how wearables are poised to transform medicine.

Watch Dr. Schadt’s presentation “From Big Data to Predictive Models of Disease (A Multiscale Biology View)” at the 2013 UAB Comprehensive Cancer Center Systems Biomedicine Symposium.”

Watch Dr. Schadt’s 2013 CSHL keynote speech “Considering the Digital Universe of Data to Better Diagnose and Treat Patients.”

Watch Dr. Schadt’s 2011 TEDMED presentation and subsequent Q&A.